PhD studentship: Exploring development and evolution of the maternal and infant skin microbiome

Quadram Institute Bioscience

 

Applications Close: 30 April 2020
Salary: Stipend of £19,285
Contract Length: 3 years

The Hall Lab, based within the Quadram Institute is looking for a creative and enthusiastic PhD candidate to join a dynamic, multi-disciplinary research team investigating the interactions of the host with the microbiota during the early life developmental window. The Hall lab is a new interdisciplinary microbiome and food research Institute, thus providing an excellent platform for a starting scientific career. This studentship also represents and exciting academic-industry collaboration with Unilever, who have a keen interest in exploring and exploiting the microbiome for development of new treatments.

Background: Human skin faces constant external challenge. While skin has evolved to combat insults such as infection and pollution a key element of its defence is the human microbiome, the first layer of protection. Despite the increasing recognition of the importance of the skin microbiome health there has been little investigation of the baby skin microbiome, and almost no investigation of the longitudinal development of that microbiome after birth.

This project seeks to investigate the development and evolution of the human skin microbiome while gaining a greater understanding of the impact that microbial disturbances in early years can have on skin health. These insights will be essential to the formulation of the next generation of skin care products to maintain skin health across the life course.

The multi-disciplinary project, using samples from PEARL, an ongoing pregnancy and infant cohort, will involve a combination of wet and dry lab techniques/skills including; next generation sequencing, bioinformatics, microbial culturing, and cell culture.

For further information and to apply, please visit the Quadram Institute website.