CORE UNIVERSITY

University of Nottingham

Research Areas & Focuses

  1. Quorum sensing singalling in biofilms
  2. In vitro and in vivo biofilm models, human skin, mouse catheter, histology
  3. Drug discovery, medicinal chemistry, structural biology
  4. Polymicrobial biofilm interactions
  5. Biofilm human host interactions
  6. Mechanisms of biofilm surface interactions
  7. Chemical analysis of surfaces and biofilms
  8. Novel Biofilm Target Discovery
  9. Mechanisms of biofilm formation and dispersal
  10. High throughput screening of antibiofilm surfaces – polymer arrays
  11. MRI detection of biofilms

University of Nottingham

For enquiries, please contact Miguel Cámara.

Facilities

  • Cryo 3D Orbi-SIMS, ToF-SIMS, Nanoscale and Microscale Research Centre (NMRC)
  • Managed Curated Chemical Compound Library
  • Advanced microscopy and Super Resolution (SLIM) including Electron microscopy, Fluorescence microscopy, histology and light microscopy, confocol microscope
  • Ivis Spectrum (SPOT)
  • Automated High throughput screening Robot (Synthetic Biology Research Centre)
  • Centre for Additive Manufacturing (CfAM)
  • Spray and cold gas dynamic spray-based surface coatings
  • Sir Peter Mansfield Imaging Centre (SPMIC)

Researchers

Morgan Alexander, Pharmacy
Steve Atkinson, Life Sciences
Jon Aylott, Pharmacy
Serafim Bakalis, Food Process Engineering
Michael Barlow, Physics
Helen Barr, Medicine (Respiratory)
Dave Barrett, Pharmacy
Laura Barrientos Moreno, Life Sciences
Roger Bayston, Medicine
Samantha Bryan, Life Sciences
Miguel Cámara, Life Sciences
Sue Clayton, Research and Innovation
Ian Connerton, Biosciences
Alex Conradie, Engineering
Georgios Dimitrakis, Chemical and Environmental Engineering
Adam Dundas, Advanced Materials Research Group
Ahmad Elsahn, Opthalmology
Richard Emes, Vet School
Jonas Emsley, Pharmacy
Helena Gomes, Engineering
Rachel Gomes, Engineering
Richard Hague, Mechanical, Materials and Manufacturing Engineering
Nigel Halliday, Life Sciences
Kim Hardie, Life Sciences
Stephan Heeb, Life Sciences
Buddi Hewakandamby, Chemical Engineering
Laura Hobley, Biosciences
Andrew Hook, Pharmacy
Tanvir Hussain, Engineering
Derek Irvine, Pharmacy
John King, Mathematical Sciences
Sergiy Korposh, Electrical and Electronic Engineering
Christina Lee, English
Kelly Lee, Life Sciences
James Leigh, Vet School
Gaston Lopez, Life Sciences
Simone Lucanto, Life Sciences
Robert Markus, Life Sciences
Luisa Martinez-Pomares, Life Sciences
Celia Mayer Mayer, Life Sciences
Nigel Minton, Life Sciences
Nick Mitchell, Chemistry
Stephen Morgan, Electrical and Electronic Engineering
Paolo Pantalone, Life Sciences
Galina Pavlovskaya, Medicine
Andrew Prayle, Medicine
David Quain, Biosciences
Clive Roberts, Pharmacy
Shaun Robertson, Life Sciences
Manuel Romero, Life Sciences
Felicity Rose, Pharmacy
Tim Self, Life Sciences
Alan Smyth, Medicine (Child Health)
Fadi Soukarieh, Life Sciences
Michael Stocks, Pharmacy
Nicholas Watson, Chemical and Environmental Engineering
Fiona Whelan, Life Sciences
Ricky Wildman, Engineering
Paul Williams, Life Sciences
Phil Williams, Pharmacy
Iona Willingham, Life Sciences
Klaus Winzer, Life Sciences

Robotic Platforms

The robotic suite is a custom-made system that consist of two interconnected robotic platforms located in the synthetic biology research centre (SBRC). The robotic system allows for the setup of customized protocols and workflows. It gives a wide range of options for gene assembly, microbial transformation (chemical and HT electroporation), colony plating and picking, transformant library screening, purification of nucleic acid, proteins and analytes, size section of DNA bands, high throughput electrophoresis and screening of compound libraries.

3D OrbiSIMS

A Time of Flight Secondary Ion Mass Spectrometer (ToF-SIMS) with hybrid OrbiTrap functionality, the ‘3D OrbiSIMS’ is the first of its kind in an academic setting. Based on the prototype at the National Physical Laboratory (NPL) the instrument combines the function of the two hybridised components to facilitate an unprecedented level of mass spectral molecular analysis for a range of materials (hard and soft matter, biological cells and tissues).

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